Blocking ELISA’s for the distinction between antibodies against European and American strains of porcine reproductive and respiratory syndrome virus.

Description: Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.

Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

Description: Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

Description: The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilization rates. Knockout females also display a reduced number of primary follicles.

Description: Human ErbB4 (Her4), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001036064.1)

Description: Human ErbB4 (Her4), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001036064.1)

Description: Human ErbB4 (Her4), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005226.1)

Description: Human ErbB4 (Her4), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005226.1)

Description: Mycobacterium Leprae Putative primosomal protein N'(priA), recombinant protein.

Description: Yersinia Enterocolitica Invasin, recombinant protein.

Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Description: Echinococcus Granulosus 78 kDa glucose-regulated protein (GRP78), partial, recombination protein.

Description: Brucella Abortus (strain 2308) Probable potassium transport system protein kup, recombinant protein.

Description: Brucella Ovis (strain ATCC 25840 / 63/290 / NCTC 10512) Acetyl-coenzyme A synthetase, recombinant protein.

Description: Brucella Suis (strain ATCC 23445 / NCTC 10510) Acetyl-coenzyme A synthetase, recombinant protein.

Description: Haemophilus Influenzae (strain PittEE) Electron transport complex protein RnfC, recombinant protein.

Description: Recombinant Human ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 97.5 kDa. (Accession ID: NP_001036064.1)

Description: Recombinant Human ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 97.5 kDa. (Accession ID: NP_001036064.1)

Description: Recombinant Rat ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.3 kDa. (Accession ID: AAQ77349.1)

Description: Recombinant Rat ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.3 kDa. (Accession ID: AAQ77349.1)

Description: Recombinant Rat ErbB4 Protein (Met1-Pro651) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.9 kDa. (Accession ID: AAQ77349.1)

Description: Recombinant Rat ErbB4 Protein (Met1-Pro651) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.9 kDa. (Accession ID: AAQ77349.1)

Description: Mycobacterium Gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) Chaperone protein htpG (htpG), recombinant protein.

Description: Mycobacterium Vanbaalenii (strain DSM 7251 / PYR-1) Chaperone protein htpG (htpG), recombinant protein.

Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) p-hydroxybenzoic acid efflux pump subunit AaeB (aaeB), recombinant protein.

Description: This ADC product is comprised of an anti-ACVR2B monoclonal antibody conjugated via a SPDB linker to DM4